PKC gamma 抗体 (C-Term)
Quick Overview for PKC gamma 抗体 (C-Term) (ABIN391009)
抗原
See all PKC gamma (PRKCG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 305-336, C-Term
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预测反应
- Pr
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This PKC gamma antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-336 amino acids from the C-terminal region of human PKC gamma.
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亚型
- Ig Fraction
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anti-Protein Kinase C, gamma (PRKCG) (pThr514) antibody
PRKCG 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 260-351) antibodyPRKCG 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (Internal Region) antibodyPRKCG 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (Thr655) antibodyPRKCG 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 1-314) antibodyPRKCG 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 71-120) antibodyPRKCG 适用: 人, 大鼠, 小鼠, Cow, 兔, 犬, 豚鼠, 马, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 539-588) antibodyPRKCG 适用: 人, 大鼠, 小鼠, Cow, 兔, 犬, 豚鼠, 马, 猴, 斑马鱼, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (N-Term) antibodyPRKCG 适用: 人 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (N-Term) antibodyPRKCG 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 665-685), (C-Term) antibodyPRKCG 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))
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别名
- PKC gamma
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背景
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC gamma is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).
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分子量
- 78448
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基因ID
- 5582
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NCBI登录号
- NP_002730
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UniProt
- P05129
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途径
- WNT signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGF Signaling
抗原
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