PKC epsilon 抗体 (N-Term)
(1 reference)Quick Overview for PKC epsilon 抗体 (N-Term) (ABIN391007)
抗原
See all PKC epsilon (PRKCE) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 206-236, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This PKC epsilon antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-236 amino acids from the N-terminal region of human PKC epsilon.
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亚型
- Ig Fraction
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anti-Protein Kinase C, epsilon (PRKCE) (AA 631-737) antibody
PRKCE 适用: 人, 大鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) antibodyPRKCE 适用: 人, 猴, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2A12 unconjugated
anti-Protein Kinase C, epsilon (PRKCE) antibodyPRKCE 适用: 人, 猴, 犬 IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 488-737) antibodyPRKCE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 403-672) antibodyPRKCE 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) antibodyPRKCE 适用: 人, 猴, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 2E9 unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 403-672) antibodyPRKCE 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 53-236) antibodyPRKCE 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 301-400) antibodyPRKCE 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 206-236), (N-Term) antibodyPRKCE 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Activated PKC{delta} and PKC{epsilon} inhibit epithelial chloride secretion response to cAMP via inducing internalization of the Na+-K+-2Cl- cotransporter NKCC1." in: The Journal of biological chemistry, Vol. 285, Issue 44, pp. 34072-85, (2010) (PubMed).
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: "Activated PKC{delta} and PKC{epsilon} inhibit epithelial chloride secretion response to cAMP via inducing internalization of the Na+-K+-2Cl- cotransporter NKCC1." in: The Journal of biological chemistry, Vol. 285, Issue 44, pp. 34072-85, (2010) (PubMed).
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- PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))
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别名
- PKC epsilon
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背景
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC epsilon is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.
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分子量
- 83674
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基因ID
- 5581
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NCBI登录号
- NP_005391
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UniProt
- Q02156
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途径
- TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
抗原
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