PKC beta 抗体 (C-Term)
(1 reference)Quick Overview for PKC beta 抗体 (C-Term) (ABIN391003)
抗原
See all PKC beta (PRKCB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 642-673, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This PKC beta2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 642-673 amino acids from the C-terminal region of human PKC beta2.
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亚型
- Ig Fraction
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anti-Protein Kinase C, beta (PRKCB) (AA 1-270) antibody
PRKCB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, beta (PRKCB) (AA 220-340) antibodyPRKCB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, beta (PRKCB) (pThr500) antibodyPRKCB 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, beta (PRKCB) (AA 517-643) antibodyPRKCB 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, beta (PRKCB) (pThr641) antibodyPRKCB 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, beta (PRKCB) (Internal Region) antibodyVerified PRKCB 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Protein Kinase C, beta (PRKCB) (AA 642-673) antibodyPRKCB 适用: 人, 大鼠, 小鼠, 灵长类 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, beta (PRKCB) (AA 601-673) antibodyPRKCB 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, beta (PRKCB) (AA 261-341) antibodyPRKCB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase C, beta (PRKCB) (AA 1-671) antibodyPRKCB 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Human biliverdin reductase, a previously unknown activator of protein kinase C betaII." in: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 8110-22, (2007) (PubMed).
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: "Human biliverdin reductase, a previously unknown activator of protein kinase C betaII." in: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 8110-22, (2007) (PubMed).
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- PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))
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别名
- PKC beta2
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背景
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC beta is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. Isoform 1 uses an alternate exon at the 3' end compared to isoform 2, which includes a part of the coding region. The resulting isoform 1 has a distinct and shorter C-terminus, as compared to isoform 2.
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基因ID
- 5579
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途径
- WNT signaling, TCR Signaling, Thyroid Hormone Synthesis, Nuclear Hormone Receptor Binding, Chromatin Binding, Myometrial Relaxation and Contraction, VEGF Signaling, Unfolded Protein Response, BCR Signaling
抗原
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