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MLF1 抗体 (N-Term)

This anti-MLF1 antibody is a 兔 多克隆 antibody detecting MLF1 in WB. Suitable for 人 和 小鼠.
产品编号 ABIN390672
发货至: 中国
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Quick Overview for MLF1 抗体 (N-Term) (ABIN390672)

抗原

See all MLF1 抗体
MLF1 (Myeloid Leukemia Factor 1 (MLF1))

适用

  • 64
  • 44
  • 20
  • 1
  • 1
人, 小鼠

宿主

  • 61
  • 5

克隆类型

  • 63
  • 3
多克隆

标记

  • 35
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MLF1 antibody is un-conjugated

应用范围

  • 53
  • 21
  • 21
  • 16
  • 13
  • 8
  • 7
  • 4
  • 3
  • 3
  • 2
Western Blotting (WB)

克隆位点

RB18642
  • 抗原表位

    • 13
    • 8
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-62, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This MLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-62 amino acids from the N-terminal region of human MLF1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    MLF1 (Myeloid Leukemia Factor 1 (MLF1))

    别名

    MLF1

    背景

    MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

    分子量

    30627

    基因ID

    4291

    NCBI登录号

    NP_001123628, NP_001123629, NP_001182361, NP_001182362, NP_001182363, NP_071888

    UniProt

    P58340
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