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PARK7/DJ1 抗体 (N-Term)

This anti-PARK7/DJ1 antibody is a 兔 多克隆 antibody detecting PARK7/DJ1 in WB 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN390371
发货至: 中国

Quick Overview for PARK7/DJ1 抗体 (N-Term) (ABIN390371)

抗原

See all PARK7/DJ1 (PARK7) 抗体
PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

适用

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人, 小鼠

宿主

  • 113
  • 23
  • 2
  • 1

克隆类型

  • 108
  • 31
多克隆

标记

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This PARK7/DJ1 antibody is un-conjugated

应用范围

  • 114
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  • 23
  • 14
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  • 5
  • 5
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Western Blotting (WB), Immunofluorescence (IF)

克隆位点

RB8160
  • 抗原表位

    • 29
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    • 1
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    AA 1-30, N-Term

    预测反应

    B, Zf

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This DJ-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DJ-1.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:2000. WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

    别名

    DJ-1

    背景

    Park 7 acts as positive regulator of androgen receptor-dependent transcription, and may function as redox-sensitive chaperone and as sensor for oxidative stress, as well as preventing aggregation of SNCA. This protein has been shown to protect neurons against oxidative stress and cell death, and to play a role in fertilization. Park7 is detected in tau inclusions in brains from neurodegenerative disease patients, and is generally highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, with detectable levels in placenta, brain, astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa. Defects in Park7 are the cause of autosomal recessive early-onset Parkinson disease 7 (PARK7), a form of Parkinson disease characterized by onset before 40 years, slow progression and initial good response to levodopa.

    分子量

    19891

    基因ID

    11315

    NCBI登录号

    NP_001116849, NP_009193

    UniProt

    Q99497

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
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