ZBTB7B 抗体 (AA 181-210)
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北京 101111
Quick Overview for ZBTB7B 抗体 (AA 181-210) (ABIN390349)
抗原
See all ZBTB7B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 181-210
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This ZBTB7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-210 amino acids from the Central region of human ZBTB7B.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))
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别名
- ZBTB7B
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背景
- ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.
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分子量
- 58027
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基因ID
- 51043
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NCBI登录号
- NP_001239335, NP_001243384
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UniProt
- O15156
抗原
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