OAS3 抗体 (C-Term)
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北京 101111
Quick Overview for OAS3 抗体 (C-Term) (ABIN390166)
抗原
See all OAS3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1056-1087, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This OAS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1056-1087 amino acids from the C-terminal region of human OAS3.
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亚型
- Ig Fraction
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anti-2'-5' Oligoadenylate Synthetase 3 (OAS3) (AA 320-620) antibody
OAS3 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-2'-5' Oligoadenylate Synthetase 3 (OAS3) (AA 424-565) antibodyOAS3 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-2'-5' Oligoadenylate Synthetase 3 (OAS3) antibodyOAS3 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-2'-5' Oligoadenylate Synthetase 3 (OAS3) antibodyOAS3 适用: 人, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "The 2'-5'-oligoadenylate synthetase 3 enzyme potently synthesizes the 2'-5'-oligoadenylates required for RNase L activation." in: Journal of virology, Vol. 88, Issue 24, pp. 14222-31, (2014) (PubMed).
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: "The 2'-5'-oligoadenylate synthetase 3 enzyme potently synthesizes the 2'-5'-oligoadenylates required for RNase L activation." in: Journal of virology, Vol. 88, Issue 24, pp. 14222-31, (2014) (PubMed).
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- OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))
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别名
- OAS3
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背景
- OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2',5'-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.
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分子量
- 121170
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基因ID
- 4940
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NCBI登录号
- NP_006178
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UniProt
- Q9Y6K5
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途径
- Hepatitis C
抗原
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