Nanog 抗体 (pSer285)
Our Local Distributor
北京 101111
Quick Overview for Nanog 抗体 (pSer285) (ABIN390033)
抗原
See all Nanog (NANOG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- pSer285
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This Nanog Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S285 of human Nanog.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- DB: 1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
- Nanog (NANOG) (Nanog Homeobox (NANOG))
-
别名
- Nanog
-
背景
- NANOG is a Ttranscription regulator involved in inner cell mass and embryonic stem (ES) cels proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation.
-
分子量
- 34620
-
基因ID
- 79923
-
NCBI登录号
- NP_079141
-
UniProt
- Q9H9S0
-
途径
- Stem Cell Maintenance
抗原
-