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Nanog 抗体 (pSer71)

This anti-Nanog antibody is a 兔 多克隆 antibody detecting Nanog in IF 和 DB. Suitable for 人.
产品编号 ABIN390032
发货至: 中国

Quick Overview for Nanog 抗体 (pSer71) (ABIN390032)

抗原

See all Nanog (NANOG) 抗体
Nanog (NANOG) (Nanog Homeobox (NANOG))

适用

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宿主

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克隆类型

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多克隆

标记

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This Nanog antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Dot Blot (DB)

克隆位点

RB18920
  • 抗原表位

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    pSer71

    预测反应

    Pr

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Nanog Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S71 of human Nanog.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    Nanog (NANOG) (Nanog Homeobox (NANOG))

    别名

    Nanog

    背景

    NANOG is a Ttranscription regulator involved in inner cell mass and embryonic stem (ES) cels proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation.

    分子量

    34620

    基因ID

    79923

    NCBI登录号

    NP_079141

    UniProt

    Q9H9S0

    途径

    Stem Cell Maintenance
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