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c-MYC 抗体 (pThr58)

This anti-c-MYC antibody is a 兔 多克隆 antibody detecting c-MYC in WB 和 DB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN389723
发货至: 中国

Quick Overview for c-MYC 抗体 (pThr58) (ABIN389723)

抗原

See all c-MYC (MYC) 抗体
c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

适用

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宿主

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克隆类型

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多克隆

标记

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This c-MYC antibody is un-conjugated

应用范围

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Western Blotting (WB), Dot Blot (DB)

克隆位点

RB11187
  • 抗原表位

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    pThr58

    预测反应

    X, Zf, M, Rat, B, Pig, Sh

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MYC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Yeh, Lu, Ou, Cheng: "I?B kinases increase Myc protein stability and enhance progression of breast cancer cells." in: Molecular cancer, Vol. 10, pp. 53, (2011) (PubMed).

  • 抗原

    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

    别名

    Myc Proto-Oncogene protein

    背景

    MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.

    分子量

    48804

    基因ID

    4609

    NCBI登录号

    NP_002458

    UniProt

    P01106

    途径

    p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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