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SMAD4 抗体 (pThr277)

Cited in 1 publication. This 兔 多克隆 anti-SMAD4 antibody (Clone RB07971) specifically detects SMAD4 in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN389658
发货至: 中国
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Quick Overview for SMAD4 抗体 (pThr277) (ABIN389658)

抗原

See all SMAD4 抗体
SMAD4 (SMAD Family Member 4 (SMAD4))

适用

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人, 小鼠

宿主

  • 86
  • 20
  • 1
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克隆类型

  • 60
  • 48
多克隆

标记

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  • 1
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This SMAD4 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB07971
  • 抗原表位

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    • 4
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    • 2
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    pThr277

    预测反应

    Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This SMAD4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Arjunan, Gnanaprakasam, Ananth, Romej, Rajalakshmi, Prasad, Martin, Gurusamy, Thangaraju, Bhutia, Ganapathy: "Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis." in: Investigative ophthalmology & visual science, Vol. 57, Issue 4, pp. 1612-9, (2016) (PubMed).

  • 抗原

    SMAD4 (SMAD Family Member 4 (SMAD4))

    别名

    SMAD4

    背景

    Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.

    分子量

    60439

    基因ID

    4089

    NCBI登录号

    NP_005350

    UniProt

    Q13485

    途径

    Cell Division Cycle, Chromatin Binding, Autophagy
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