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CDC25A 抗体 (pSer124)

Name: CDC25A 抗体 (pSer124)
SKU: ABIN389527
Availability: OutOfStock

This anti-CDC25A antibody is a 兔多克隆 antibody detecting CDC25A in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.

Western blot analysis of lysates from cell line, untreated or treated with Alkaline phosphatase, 1h, using 459085101 A (upper) or Beta-actin (lower). (CDC25A 抗体 (pSer124))

Immunohistochemical analysis of A on paraffin-embedded Human breast carcinoma tissue. (CDC25A 抗体 (pSer124))

IHC (p)

Western blot analysis of lysates from cell line, untreated or treated with Alkaline phosphatase, 1h, using 459088101 A (upper) or Beta-actin (lower). (CDC25A 抗体 (pSer124))

Western blot analysis of lysates from 293 cell line, untreated or treated with Alkaline phosphatase, 1h, using 459088102 A (upper) or Beta-actin (lower). (CDC25A 抗体 (pSer124))

The anti-phospho CDC25A Pab (ABIN389527 and ABIN2839576) is used in Western blot to detect CDC25A in mouse liver tissue lysate (CDC25A 抗体 (pSer124))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (CDC25A 抗体 (pSer124))

IHC (p)

6 images

(2 references)

产品编号 ABIN389527

发货至: 中国

Datasheet as PDF

Quick Overview for CDC25A 抗体 (pSer124) (ABIN389527)

抗原

See all CDC25A 抗体

CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

适用

人

宿主

兔

克隆类型

多克隆

标记

This CDC25A antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB07634

Discover our top product CDC25A Primary Antibody

抗原表位
31

26

19

17

15

13

9

9

8

8

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7

5

4

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer124

预测反应

Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This CDC25A Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S124 of human CDC25A.

亚型

Ig Fraction
anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (AA 235-484) antibody
CDC25A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pSer75) antibody
CDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pThr507) antibody
CDC25A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (AA 1-524) antibody
CDC25A 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pSer124) antibody
CDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pThr507) antibody
CDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pSer178) antibody
CDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (N-Term) antibody
CDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (Ser124) antibody
CDC25A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB59086 unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (AA 151-250) antibody
CDC25A 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3D5 unconjugated

应用备注

WB: 1:500. WB: 1:500. WB: 1:500. WB: 1:1000. IHC-P: 1:100. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Zoppoli, Solier, Reinhold, Liu, Connelly, Monks, Shoemaker, Abaan, Davis, Meltzer, Doroshow, Pommier: "CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute." in: Oncogene, Vol. 31, Issue 4, pp. 403-18, (2012) (PubMed).

Solier, Sordet, Kohn, Pommier: "Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways." in: Molecular and cellular biology, Vol. 29, Issue 1, pp. 68-82, (2008) (PubMed).
抗原

CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

别名

CDC25A

背景

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

分子量

59087

基因ID

993

NCBI登录号

NP_001780, NP_963861

UniProt

P30304

途径

Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase