APRT 抗体 (C-Term)
Quick Overview for APRT 抗体 (C-Term) (ABIN389427)
抗原
See all APRT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 143-170, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This APRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-170 amino acids from the C-terminal region of human APRT.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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Adenine phosphoribosyltransferase (APRT) deficiency: identification of a novel nonsense mutation." in: BMC nephrology, Vol. 15, pp. 102, (2014) (PubMed).
: "
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Adenine phosphoribosyltransferase (APRT) deficiency: identification of a novel nonsense mutation." in: BMC nephrology, Vol. 15, pp. 102, (2014) (PubMed).
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- APRT (Adenine Phosphoribosyltransferase (APRT))
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别名
- APRT
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背景
- A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.
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分子量
- 19608
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基因ID
- 353
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NCBI登录号
- NP_000476, NP_001025189
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UniProt
- P07741
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途径
- Ribonucleoside Biosynthetic Process
抗原
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