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APRT 抗体 (N-Term)

Cited in 1 publication. This anti-APRT antibody is a 兔 多克隆 antibody detecting APRT in WB, IF, FACS 和 IHC (p). Suitable for 人.
产品编号 ABIN389426
发货至: 中国
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Quick Overview for APRT 抗体 (N-Term) (ABIN389426)

抗原

See all APRT 抗体
APRT (Adenine Phosphoribosyltransferase (APRT))

适用

  • 50
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宿主

  • 47
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克隆类型

  • 49
  • 1
多克隆

标记

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This APRT antibody is un-conjugated

应用范围

  • 36
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  • 9
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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB20509
  • 抗原表位

    • 14
    • 7
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    AA 12-40, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This APRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human APRT.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Valaperta, Rizzo, Lombardi, Verdelli, Piccoli, Ghiroldi, Creo, Colombo, Valisi, Margiotta, Panella, Costa: "Adenine phosphoribosyltransferase (APRT) deficiency: identification of a novel nonsense mutation." in: BMC nephrology, Vol. 15, pp. 102, (2014) (PubMed).

  • 抗原

    APRT (Adenine Phosphoribosyltransferase (APRT))

    别名

    APRT

    背景

    A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.

    分子量

    19608

    基因ID

    353

    NCBI登录号

    NP_000476, NP_001025189

    UniProt

    P07741

    途径

    Ribonucleoside Biosynthetic Process
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