Endoglin 抗体 (AA 380-409)
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Quick Overview for Endoglin 抗体 (AA 380-409) (ABIN389408)
抗原
See all Endoglin (ENG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 380-409
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CD105 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-409 amino acids from the Central region of human CD105.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- Endoglin (ENG)
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别名
- CD105
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背景
- CD105 is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in its gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
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分子量
- 70578
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基因ID
- 2022
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NCBI登录号
- NP_000109, NP_001108225, NP_001265067
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UniProt
- P17813
抗原
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