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Ataxin 1 抗体 (AA 754-781)

This anti-Ataxin 1 antibody is a 兔 多克隆 antibody detecting Ataxin 1 in WB 和 IF. Suitable for 人.
产品编号 ABIN389309
发货至: 中国

Quick Overview for Ataxin 1 抗体 (AA 754-781) (ABIN389309)

抗原

See all Ataxin 1 (ATXN1) 抗体
Ataxin 1 (ATXN1)

适用

  • 79
  • 63
  • 35
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 66
  • 52
  • 1

克隆类型

  • 66
  • 53
多克隆

标记

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  • 7
  • 5
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  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Ataxin 1 antibody is un-conjugated

应用范围

  • 88
  • 45
  • 44
  • 36
  • 33
  • 25
  • 23
  • 23
  • 9
  • 6
  • 6
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)

克隆位点

RB16258
  • 抗原表位

    • 28
    • 22
    • 17
    • 12
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 754-781

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ATXN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 754-781 amino acids from human ATXN1.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    Ataxin 1 (ATXN1)

    别名

    ATXN1

    背景

    The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known.

    分子量

    86923

    基因ID

    6310

    NCBI登录号

    NP_000323, NP_001121636

    UniProt

    P54253

    途径

    Synaptic Membrane
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