LGR5 抗体 (AA 443-473)
Quick Overview for LGR5 抗体 (AA 443-473) (ABIN389219)
抗原
See all LGR5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 443-473
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预测反应
- B
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This LGR5 (GPR49) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 443-473 amino acids from the Central region of human LGR5 (GPR49).
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000. IHC: 1:100. IHC-P: 1:10~50. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Multiple roles of integrin-linked kinase in epidermal development, maturation and pigmentation revealed by molecular profiling." in: PLoS ONE, Vol. 7, Issue 5, pp. e36704, (2012) (PubMed).
: "LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines." in: PLoS ONE, Vol. 6, Issue 7, pp. e22733, (2011) (PubMed).
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: "Multiple roles of integrin-linked kinase in epidermal development, maturation and pigmentation revealed by molecular profiling." in: PLoS ONE, Vol. 7, Issue 5, pp. e36704, (2012) (PubMed).
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- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
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别名
- LGR5 (GPR49)
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背景
- LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues.
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分子量
- 99998
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基因ID
- 8549
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NCBI登录号
- NP_001264155, NP_003658
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UniProt
- O75473
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途径
- WNT signaling
抗原
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