MIB1 抗体 (N-Term)
Quick Overview for MIB1 抗体 (N-Term) (ABIN388956)
抗原
See all MIB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 13-42, N-Term
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预测反应
- Zf, M
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This Mib1/Mindbomb antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human Mib1/Mindbomb.
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亚型
- Ig Fraction
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anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 6-221) antibody
MIB1 适用: 人, 猴 ELISA, WB, ICC, FACS 宿主: 小鼠 Monoclonal 6A9C9 unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 5-332) antibodyMIB1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 901-950) antibodyMIB1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 769-1000) antibodyMIB1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 909-1006) antibodyMIB1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 909-1006) antibodyMIB1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3E10 unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 560-860) antibodyMIB1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (C-Term) antibodyMIB1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (N-Term) antibodyMIB1 适用: Drosophila melanogaster ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (N-Term) antibodyMIB1 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF: 1:20~100. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
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别名
- Mib1/Mindbomb
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背景
- MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.
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分子量
- 110136
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基因ID
- 57534
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NCBI登录号
- NP_065825
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UniProt
- Q86YT6
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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