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USP20 抗体 (C-Term)

This anti-USP20 antibody is a 兔 多克隆 antibody detecting USP20 in WB 和 IHC (p). Suitable for 小鼠.
产品编号 ABIN388910
发货至: 中国

Quick Overview for USP20 抗体 (C-Term) (ABIN388910)

抗原

See all USP20 抗体
USP20 (Ubiquitin Specific Peptidase 20 (USP20))

适用

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小鼠

宿主

  • 33
  • 4
  • 1

克隆类型

  • 37
  • 1
多克隆

标记

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This USP20 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB4351
  • 抗原表位

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    AA 814-844, C-Term

    预测反应

    B

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This USP20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 814-844 amino acids from the C-terminal region of human USP20.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    USP20 (Ubiquitin Specific Peptidase 20 (USP20))

    别名

    USP20

    背景

    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

    分子量

    102003

    基因ID

    10868

    NCBI登录号

    NP_001008563, NP_001103773, NP_006667

    UniProt

    Q9Y2K6

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling
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