USP14 抗体 (N-Term)
(1 reference)Quick Overview for USP14 抗体 (N-Term) (ABIN388902)
抗原
See all USP14 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-30, N-Term
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预测反应
- B, M
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This USP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human USP14.
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亚型
- Ig Fraction
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anti-Ubiquitin Specific Peptidase 14 (USP14) (AA 395-494) antibody
USP14 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6D6 unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) (AA 395-494) antibodyUSP14 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) (AA 1-494), (C-Term) antibodyUSP14 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) (AA 1-494) antibodyUSP14 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) antibodyUSP14 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) antibodyUSP14 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 9C1 unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) (AA 1-494) antibodyUSP14 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) antibodyUSP14 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) (AA 355-383), (C-Term) antibodyUSP14 适用: 人 WB 宿主: 兔 Polyclonal RB41691 unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) (N-Term) antibodyUSP14 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation." in: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5742-52, (2009) (PubMed).
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: "Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation." in: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5742-52, (2009) (PubMed).
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- USP14 (Ubiquitin Specific Peptidase 14 (USP14))
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别名
- USP14
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背景
- Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
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分子量
- 56069
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基因ID
- 9097
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NCBI登录号
- NP_001032411, NP_005142
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UniProt
- P54578
抗原
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