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USP8 抗体 (N-Term)

This anti-USP8 antibody is a 兔 多克隆 antibody detecting USP8 in WB. Suitable for 人.
产品编号 ABIN388890
发货至: 中国

Quick Overview for USP8 抗体 (N-Term) (ABIN388890)

抗原

See all USP8 抗体
USP8 (Ubiquitin Specific Peptidase 8 (USP8))

适用

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宿主

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克隆类型

  • 35
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多克隆

标记

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This USP8 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB4284
  • 抗原表位

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    AA 1-30, N-Term

    预测反应

    M

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This USP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human USP8.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    USP8 (Ubiquitin Specific Peptidase 8 (USP8))

    别名

    USP8

    背景

    USP8 is a ubiquitin specific protease that plays an important regulatory role at the level of protein turnover by preventing degradation. USP8 is involved in cell proliferation, and probably regulates the stability of STAM2 and RASGRF1. USP8 may regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and STAM2. As revealed by structur/function studies, USP8 forms a ternary complex with RNF128 and OTUB1, and interacts with the SH3 domain of STAM2 and RASGRF1. Expression of USP8 is induced Upon growth stimulation in starved human fibroblasts, and expression decreases in response to growth arrest induced by cell-cell contact.

    分子量

    127523

    基因ID

    9101

    NCBI登录号

    NP_001122082, NP_001122083, NP_005145

    UniProt

    P40818
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