SKP1 抗体 (AA 58-87)
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北京 101111
Quick Overview for SKP1 抗体 (AA 58-87) (ABIN388650)
抗原
See all SKP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 58-87
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预测反应
- B, C, Pr, M, Rat, X
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This SKP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the Central region of human SKP1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))
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别名
- SKP1
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背景
- SKP1A is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. SKP1A also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor.
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分子量
- 18658
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基因ID
- 6500
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NCBI登录号
- NP_008861, NP_733779
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UniProt
- P63208
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途径
- Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases
抗原
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