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PIK3C3 抗体 (C-Term)

Name: PIK3C3 抗体 (C-Term)
SKU: ABIN388591
Availability: OutOfStock

This anti-PIK3C3 antibody is a 兔多克隆 antibody detecting PIK3C3 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.

Western blot analysis of lysate from U-251 MG cell line, using hPI3KC3 (C-term) (ABIN388591 and ABIN2849999). (PIK3C3 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with hPI3KC3 (C-term) (ABIN388591 and ABIN2849999) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (PIK3C3 抗体 (C-Term))

IHC (p)

2 images

(2 references)

产品编号 ABIN388591

发货至: 中国

Quick Overview for PIK3C3 抗体 (C-Term) (ABIN388591)

抗原

See all PIK3C3 抗体

PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

适用

人

宿主

兔

克隆类型

多克隆

标记

This PIK3C3 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB10857

Discover our top product PIK3C3 Primary Antibody

抗原表位
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AA 770-801, C-Term

预测反应

M, Pig, Rat

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This PI3KC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 770-801 amino acids from the C-terminal region of human PI3KC3.
anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (AA 631-885) antibody
PIK3C3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (pSer164) antibody
PIK3C3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (pSer282) antibody
PIK3C3 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (AA 14-39) antibody
PIK3C3 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB11895 unconjugated

anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (AA 301-400) antibody
PIK3C3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (AA 700-850), (Catalytic Subunit) antibody
PIK3C3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (AA 150-250) antibody
PIK3C3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) antibody
PIK3C3 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (AA 24-53), (N-Term) antibody
PIK3C3 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB1695 unconjugated

anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (AA 19-49) antibody
PIK3C3 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Delaney, Patel, Willis, Haghighiabyaneh, Axelrod, Tancioni, Lu, Bapat, Young, Cadassou, Bartakova, Sheth, Haft, Hui, Saenz, Schlaepfer, Harismendy, Stupack: "Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer." in: Nature communications, Vol. 8, pp. 14423, (2017) (PubMed).

Liu, Ji, Zhou, Xing: "Phosphatidylinositol 3-Kinase Promotes Activation and Vacuolar Acidification and Delays Methyl Jasmonate-Induced Leaf Senescence." in: Plant physiology, Vol. 170, Issue 3, pp. 1714-31, (2016) (PubMed).
抗原

PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

别名

PI3KC3

背景

PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to 1-phosphatidyl-1D-myo-inositol 3-phosphate. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). The regulation of the Beclin 1-PI3KC3 complex lipid kinase activity is a critical element in the autophagy signaling pathway.

分子量

101549

基因ID

5289

NCBI登录号

NP_002638

UniProt

Q8NEB9

途径

AMPK Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Toll-Like Receptors Cascades, Autophagy