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ATG7 抗体 (AA 494-523)

Name: ATG7 抗体 (AA 494-523)
SKU: ABIN388522
Availability: OutOfStock

This anti-ATG7 antibody is a 兔多克隆 antibody detecting ATG7 in WB 和 IHC (p). Suitable for 人和小鼠. This Primary Antibody has been cited in 10+ publications.

All lanes : Anti-G7L Antibody at 1:1000 dilution Lane 1: Ba/F3 whole cell lysate Lane 2: Caki-1 whole cell lysate Lane 3: HepG2 whole cell lysate Lysates/proteins at 20 μg per lane. (ATG7 抗体 (AA 494-523))

IHC (p)

2 images

(10 references)

产品编号 ABIN388522

发货至: 中国

Quick Overview for ATG7 抗体 (AA 494-523) (ABIN388522)

抗原

See all ATG7 抗体

ATG7 (ATG7 Autophagy Related 7 (ATG7))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This ATG7 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB7472

Discover our top product ATG7 Primary Antibody

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AA 494-523

预测反应

Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This ATG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 494-523 amino acids from human ATG7.

亚型

Ig Fraction
anti-ATG7 Autophagy Related 7 (ATG7) (AA 500-676) antibody
ATG7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 477-698) antibody
ATG7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 540-569), (C-Term) antibody
ATG7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7474 unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 22-51) antibody
ATG7 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 494-523) antibody
ATG7 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) antibody
ATG7 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 558-703) antibody
ATG7 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7D3E5 unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (HRP)
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (FITC)
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC

应用备注

WB: 1:1000. IHC-P: 1:25

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Li, Zhou, Yang, Li, Zhang, Zheng: "Curcumin induces apoptotic cell death and protective autophagy in human gastric cancer cells." in: Oncology reports, Vol. 37, Issue 6, pp. 3459-3466, (2018) (PubMed).

Oikonomou, Moretti, Renga, Galosi, Borghi, Pariano, Puccetti, Palmerini, Amico, Carotti, Prezioso, Spolzino, Finocchi, Rossi, Velardi, Aversa, Napolioni, Romani: "Noncanonical Fungal Autophagy Inhibits Inflammation in Response to IFN-γ via DAPK1." in: Cell host & microbe, Vol. 20, Issue 6, pp. 744-757, (2017) (PubMed).

Gao, Li, Ding, Qi, Yang: "Cepharanthine Induces Autophagy, Apoptosis and Cell Cycle Arrest in Breast Cancer Cells." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 4, pp. 1633-1648, (2017) (PubMed).

Laggner, Pollreisz, Schmidinger, Schmidt-Erfurth, Chen: "Autophagy mediates cell cycle response by regulating nucleocytoplasmic transport of PAX6 in limbal stem cells under ultraviolet-A stress." in: PLoS ONE, Vol. 12, Issue 7, pp. e0180868, (2017) (PubMed).

Okamoto, Sakimoto, Imai, Senoo, Shidoji: "Induction of an incomplete autophagic response by cancer-preventive geranylgeranoic acid (GGA) in a human hepatoma-derived cell line." in: The Biochemical journal, Vol. 440, Issue 1, pp. 63-71, (2011) (PubMed).

Wei, Kulp, Chen: "Energy restriction as an antitumor target of thiazolidinediones." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9780-91, (2010) (PubMed).

Yang, Liu, Goga, Kim, Yuneva, Bishop: "Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 31, pp. 13836-41, (2010) (PubMed).

Bigford, Alonso, Dietrich, Keane: "A novel protein complex in membrane rafts linking the NR2B glutamate receptor and autophagy is disrupted following traumatic brain injury." in: Journal of neurotrauma, Vol. 26, Issue 5, pp. 703-20, (2009) (PubMed).

Ding, Shi, Zhou, Qiu, Xu, Dai, Shi, Wang, Ke, Wu, Fan: "Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma." in: Cancer research, Vol. 68, Issue 22, pp. 9167-75, (2008) (PubMed).

Xu, Liang, Haridas, Gaikwad, Connolly, Mills, Gutterman: "A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase." in: Cell death and differentiation, Vol. 14, Issue 11, pp. 1948-57, (2007) (PubMed).
抗原

ATG7 (ATG7 Autophagy Related 7 (ATG7))

别名

ATG7

背景

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG7 functions as an E1 enzyme essential for multisubstrates such as GABARAPL1 and ATG12. APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy.

分子量

77960

基因ID

10533

NCBI登录号

NP_001129503, NP_001138384, NP_006386

UniProt

O95352

途径

Response to Water Deprivation, Autophagy