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ATG7 抗体 (N-Term)

Name: ATG7 抗体 (N-Term)
SKU: ABIN388520
Availability: OutOfStock

This anti-ATG7 antibody is a 兔多克隆 antibody detecting ATG7 in WB 和 IHC (p). Suitable for 人和小鼠. This Primary Antibody has been cited in 3+ publications.

Western blot analysis of anti-Autophagy G7L Antibody (N-term) 1813a in 293 cell line lysates transiently transfected with the ATG7 gene (3 μg/lane). (ATG7 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with Autophagy G7L Antibody (N-term) 1813a , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (ATG7 抗体 (N-Term))

IHC (p)

G7L Antibody (E37) 1813a western blot analysis in Jurkat cell line lysates (35 μg/lane). (ATG7 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (ATG7 抗体 (N-Term))

IHC (p)

4 images

(3 references)

产品编号 ABIN388520

发货至: 中国

Quick Overview for ATG7 抗体 (N-Term) (ABIN388520)

抗原

See all ATG7 抗体

ATG7 (ATG7 Autophagy Related 7 (ATG7))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This ATG7 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB7467

Discover our top product ATG7 Primary Antibody

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AA 22-51, N-Term

预测反应

Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This ATG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from the N-terminal region of human ATG7.

亚型

Ig Fraction
anti-ATG7 Autophagy Related 7 (ATG7) (AA 500-676) antibody
ATG7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 477-698) antibody
ATG7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 540-569), (C-Term) antibody
ATG7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7474 unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 22-51) antibody
ATG7 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 494-523) antibody
ATG7 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) antibody
ATG7 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 558-703) antibody
ATG7 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7D3E5 unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (HRP)
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (FITC)
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC

应用备注

WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Wang, Hu, Sun, Zhuo, He, Wang, Yan, Liu, Luan, Dai, Yang, Huang, Zhou, Zhang, Zhai: "Down-regulation of Risa improves insulin sensitivity by enhancing autophagy." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 9, pp. 3133-45, (2017) (PubMed).

Yang, Zhao, Mei, Jiang, Geng, Li, Yao, Liu, Kong, Cao: "HMGA2 plays an important role in Cr (VI)-induced autophagy." in: International journal of cancer, Vol. 141, Issue 5, pp. 986-997, (2017) (PubMed).

Chiu, Kulp, Soni, Wang, Gunn, Schlesinger, Chen: "Eradication of intracellular Salmonella enterica serovar Typhimurium with a small-molecule, host cell-directed agent." in: Antimicrobial agents and chemotherapy, Vol. 53, Issue 12, pp. 5236-44, (2009) (PubMed).
抗原

ATG7 (ATG7 Autophagy Related 7 (ATG7))

别名

ATG7

背景

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG7 functions as an E1 enzyme essential for multisubstrates such as GABARAPL1 and ATG12. APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy.

分子量

77960

基因ID

10533

NCBI登录号

NP_001129503, NP_001138384, NP_006386

UniProt

O95352

途径

Response to Water Deprivation, Autophagy