ATG4A 抗体 (AA 1-30)
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北京 101111
Quick Overview for ATG4A 抗体 (AA 1-30) (ABIN388491)
抗原
See all ATG4A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-30
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ATG4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human ATG4A.
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亚型
- Ig Fraction
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anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 258-398) antibody
ATG4A 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8C9C2 unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 258-398) antibodyATG4A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 8E8G2 unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 289-398) antibodyATG4A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 363-392) antibodyATG4A 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7555 unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 369-398), (C-Term) antibodyATG4A 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 51-150) antibodyATG4A 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) antibodyATG4A 适用: 人 WB, IHC (p), IF, IF (cc) 宿主: 小鼠 Monoclonal 14C9 unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) antibodyATG4A 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3235 unconjugated Recombinant Antibody
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 82-111) antibodyATG4A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7553 unconjugated
anti-Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 1-214) antibodyATG4A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
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别名
- ATG4A
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背景
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4A is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP.
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分子量
- 45378
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基因ID
- 115201
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NCBI登录号
- NP_443168, NP_840054
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UniProt
- Q8WYN0
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途径
- Autophagy
抗原
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