MAP1LC3A 抗体 (AA 91-117)
Quick Overview for MAP1LC3A 抗体 (AA 91-117) (ABIN388467)
抗原
See all MAP1LC3A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 91-117
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预测反应
- Zf, B, M, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This LC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-117 amino acids from human LC3.
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亚型
- Ig Fraction
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anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 89-120), (cleaved) antibody
MAP1LC3A 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal RB38908 unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-121) antibodyMAP1LC3A 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5B10D8 unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-30), (N-Term) antibodyMAP1LC3A 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7481 unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-120) antibodyMAP1LC3A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-121) antibodyMAP1LC3A 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) antibodyMAP1LC3A 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 166AT1234 unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-30), (N-Term), (pSer12) antibodyMAP1LC3A 适用: 人 WB, DB, EIA 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 30-56) antibodyMAP1LC3A 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB11840 unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) antibodyMAP1LC3A 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-121) antibodyMAP1LC3A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7E9E12 unconjugated
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应用备注
- IF: 1:100. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
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别名
- LC3
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背景
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3a is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.
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基因ID
- 84557
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NCBI登录号
- NP_115903, NP_852610
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UniProt
- Q9H492, Q9GZQ8
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途径
- Autophagy
抗原
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