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BOK 抗体 (AA 60-90)

This anti-BOK antibody is a 兔 多克隆 antibody detecting BOK in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN388103
发货至: 中国

Quick Overview for BOK 抗体 (AA 60-90) (ABIN388103)

抗原

See all BOK 抗体
BOK (BCL2-Related Ovarian Killer (BOK))

适用

  • 41
  • 13
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  • 1
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宿主

  • 39
  • 2

克隆类型

  • 40
  • 1
多克隆

标记

  • 21
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
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  • 1
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This BOK antibody is un-conjugated

应用范围

  • 24
  • 24
  • 13
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
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  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 9
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 60-90

    预测反应

    M, Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Kurata, Yanagisawa, Ohira, Kitagawa, Nakagawara, Kamijo: "Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuroblastoma cells." in: Oncogene, Vol. 27, Issue 6, pp. 741-54, (2008) (PubMed).

    Gao, Fu, Dürrenberger, De Geyter, Zhang: "Membrane translocation and oligomerization of hBok are triggered in response to apoptotic stimuli and Bnip3." in: Cellular and molecular life sciences : CMLS, Vol. 62, Issue 9, pp. 1015-24, (2005) (PubMed).

    Yakovlev, Di Giovanni, Wang, Liu, Stoica, Faden: "BOK and NOXA are essential mediators of p53-dependent apoptosis." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28367-74, (2004) (PubMed).

  • 抗原

    BOK (BCL2-Related Ovarian Killer (BOK))

    别名

    Bok

    背景

    Bok belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains all four BCL-2 like domains (BH1, 2, 3 and 4) and is a pro-apoptotic BCL-2 protein identified in the ovary.

    基因ID

    666

    NCBI登录号

    NP_115904

    UniProt

    Q9UL32

    途径

    Positive Regulation of Endopeptidase Activity
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