BOK 抗体 (AA 60-90)
Quick Overview for BOK 抗体 (AA 60-90) (ABIN388103)
抗原
See all BOK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-90
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预测反应
- M, Rat
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuroblastoma cells." in: Oncogene, Vol. 27, Issue 6, pp. 741-54, (2008) (PubMed).
: "Membrane translocation and oligomerization of hBok are triggered in response to apoptotic stimuli and Bnip3." in: Cellular and molecular life sciences : CMLS, Vol. 62, Issue 9, pp. 1015-24, (2005) (PubMed).
: "BOK and NOXA are essential mediators of p53-dependent apoptosis." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28367-74, (2004) (PubMed).
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: "Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuroblastoma cells." in: Oncogene, Vol. 27, Issue 6, pp. 741-54, (2008) (PubMed).
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- BOK (BCL2-Related Ovarian Killer (BOK))
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别名
- Bok
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背景
- Bok belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains all four BCL-2 like domains (BH1, 2, 3 and 4) and is a pro-apoptotic BCL-2 protein identified in the ovary.
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基因ID
- 666
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NCBI登录号
- NP_115904
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UniProt
- Q9UL32
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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