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KDM3A 抗体 (N-Term)

This 兔 多克隆 anti-KDM3A antibody (Clone RB14307) specifically detects KDM3A in WB 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN387995
发货至: 中国
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Quick Overview for KDM3A 抗体 (N-Term) (ABIN387995)

抗原

See all KDM3A 抗体
KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

适用

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人, 小鼠

宿主

  • 23
  • 14

克隆类型

  • 23
  • 14
多克隆

标记

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This KDM3A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB14307
  • 抗原表位

    • 4
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    AA 50-79, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This JHDM2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human JHDM2a.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

    别名

    JHDM2a

    背景

    JHDM2a is a zinc finger protein that contains a jumonji domain. It is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. This protein preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. It is involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation.

    分子量

    147341

    基因ID

    55818

    NCBI登录号

    NP_001140160, NP_060903

    UniProt

    Q9Y4C1

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Warburg Effect
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