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IFITM3 抗体 (N-Term)

IFITM3 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB13975 unconjugated
产品编号 ABIN2845007
发货至: 中国
  • 抗原 See all IFITM3 抗体
    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
    抗原表位
    • 8
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 37
    • 6
    • 5
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 28
    • 6
    • 3
    克隆类型
    • 33
    • 4
    多克隆
    标记
    • 25
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFITM3 antibody is un-conjugated
    应用范围
    • 27
    • 19
    • 10
    • 10
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Interferon-inducible protein (IFITM3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Interferon-inducible protein (IFITM3).
    克隆位点
    RB13975
    亚型
    Ig Fraction
    Top Product
    Discover our top product IFITM3 Primary Antibody
  • 应用备注
    IF: 1:100~500. WB: 1:1000. WB: 1:2000. WB: 1:1000. IHC-P-Leica: 1:100. IHC-P-Leica: 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze-thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    有效期
    6 months
  • Savidis, Perreira, Portmann, Meraner, Guo, Green, Brass: "The IFITMs Inhibit Zika Virus Replication." in: Cell reports, Vol. 15, Issue 11, pp. 2323-30, (2017) (PubMed).

    Mäkelä, Österlund, Westenius, Latvala, Diamond, Gale, Julkunen: "RIG-I Signaling Is Essential for Influenza B Virus-Induced Rapid Interferon Gene Expression." in: Journal of virology, Vol. 89, Issue 23, pp. 12014-25, (2015) (PubMed).

    John, Chin, Perreira, Feeley, Aker, Savidis, Smith, Elia, Everitt, Vora, Pertel, Elledge, Kellam, Brass: "The CD225 domain of IFITM3 is required for both IFITM protein association and inhibition of influenza A virus and dengue virus replication." in: Journal of virology, Vol. 87, Issue 14, pp. 7837-52, (2013) (PubMed).

    Everitt, Clare, Pertel, John, Wash, Smith, Chin, Feeley, Sims, Adams, Wise, Kane, Goulding, Digard, Anttila, Baillie, Walsh, Hume, Palotie, Xue, Colonna, Tyler-Smith, Dunning, Gordon, Smyth, Openshaw et al.: "IFITM3 restricts the morbidity and mortality associated with influenza. ..." in: Nature, Vol. 484, Issue 7395, pp. 519-23, (2012) (PubMed).

    Feeley, Sims, John, Chin, Pertel, Chen, Gaiha, Ryan, Donis, Elledge, Brass: "IFITM3 inhibits influenza A virus infection by preventing cytosolic entry." in: PLoS pathogens, Vol. 7, Issue 10, pp. e1002337, (2011) (PubMed).

    Brass, Huang, Benita, John, Krishnan, Feeley, Ryan, Weyer, van der Weyden, Fikrig, Adams, Xavier, Farzan, Elledge: "The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus." in: Cell, Vol. 139, Issue 7, pp. 1243-54, (2010) (PubMed).

  • 抗原
    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
    别名
    Interferon-inducible protein (IFITM3) (IFITM3 产品)
    别名
    1110004C05Rik antibody, Cd225 antibody, Cdw217 antibody, DSPA2b antibody, Fgls antibody, IP15 antibody, mil-1 antibody, 1-8U antibody, rat8 antibody, Interferon-induced transmembrane protein 3 antibody, interferon induced transmembrane protein 3 antibody, ifm3 antibody, Ifitm3 antibody, IFITM3 antibody
    背景
    The family of interferon-induced transmembrane protein (Ifitm/mil/fragilis) cell surface proteins may modulate cell adhesion and influence cell differentiation.
    分子量
    14632
    基因ID
    10410
    NCBI登录号
    NP_066362
    UniProt
    Q01628
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