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IFITM3 抗体 (N-Term)

There are 6+ publications for this product available. The 兔多克隆 anti-IFITM3 antibody is suitable to detect IFITM3 in samples from 人和小鼠. It has been validated for WB, IF 和 IHC (p).

IFITM3 Antibody (N-term) (ABIN387989 and ABIN2845007) western blot analysis in Hela,293,A549,NCI-,HepG2,Sk-Br-3, cell line lysates (35 μg/lane). (IFITM3 抗体 (N-Term))

Immunohistochemical analysis of (ABIN387989 and ABIN2845007) on paraffin-embedded Human colon carcinoma tissue was performed on the Leica®BOND RXm. (IFITM3 抗体 (N-Term))

IHC (p)

Fluorescent confocal image of HeLa cells stained with IFITM3 (N-term) antibody. (IFITM3 抗体 (N-Term))

All lanes : Anti-IFITM3 Antibody (N-term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: 293 whole cell lysate Lane 3: HepG2 whole cell lysate Lane 4: NCI- whole cell lysate Lane 5: SK-BR-3 whole cell lysate Lane 6: human placenta lysate Lane 7: mouse colon lysate Lysates/proteins at 20 μg per lane. (IFITM3 抗体 (N-Term))

Western blot analysis of lysate from H cell line,using IFITM3 Antibody (N-term) (ABIN387989 and ABIN2845007). (IFITM3 抗体 (N-Term))

Immunohistochemical analysis of (ABIN387989 and ABIN2845007) on paraffin-embedded Human spleen tissue was performed on the Leica®BOND RXm. (IFITM3 抗体 (N-Term))

IHC (p)

6 images

(6 references)

产品编号 ABIN387989

发货至: 中国

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Quick Overview for IFITM3 抗体 (N-Term) (ABIN387989)

抗原

See all IFITM3 抗体

IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This IFITM3 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB13975

Discover our top product IFITM3 Primary Antibody

抗原表位
8

8

5

1

1

1

1

1
AA 1-30, N-Term

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This Interferon-inducible protein (IFITM3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Interferon-inducible protein (IFITM3).

亚型

Ig Fraction
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibody
IFITM3 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated

anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibody
IFITM3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibody
IFITM3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2H4-1D5 unconjugated

anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibody
IFITM3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C8-1B10 unconjugated

anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-57) antibody
IFITM3 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (Internal Region) antibody
Verified IFITM3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibody
IFITM3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (N-Term) antibody
IFITM3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (N-Term) antibody
Verified IFITM3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (N-Term) antibody
IFITM3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:100~500. WB: 1:1000. WB: 1:2000. WB: 1:1000. IHC-P-Leica: 1:100. IHC-P-Leica: 1:100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze-thaw cycles.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

有效期

6 months
Savidis, Perreira, Portmann, Meraner, Guo, Green, Brass: "The IFITMs Inhibit Zika Virus Replication." in: Cell reports, Vol. 15, Issue 11, pp. 2323-30, (2017) (PubMed).

Mäkelä, Österlund, Westenius, Latvala, Diamond, Gale, Julkunen: "RIG-I Signaling Is Essential for Influenza B Virus-Induced Rapid Interferon Gene Expression." in: Journal of virology, Vol. 89, Issue 23, pp. 12014-25, (2015) (PubMed).

John, Chin, Perreira, Feeley, Aker, Savidis, Smith, Elia, Everitt, Vora, Pertel, Elledge, Kellam, Brass: "The CD225 domain of IFITM3 is required for both IFITM protein association and inhibition of influenza A virus and dengue virus replication." in: Journal of virology, Vol. 87, Issue 14, pp. 7837-52, (2013) (PubMed).

Everitt, Clare, Pertel, John, Wash, Smith, Chin, Feeley, Sims, Adams, Wise, Kane, Goulding, Digard, Anttila, Baillie, Walsh, Hume, Palotie, Xue, Colonna, Tyler-Smith, Dunning, Gordon, Smyth, Openshaw et al.: "IFITM3 restricts the morbidity and mortality associated with influenza. ..." in: Nature, Vol. 484, Issue 7395, pp. 519-23, (2012) (PubMed).

Feeley, Sims, John, Chin, Pertel, Chen, Gaiha, Ryan, Donis, Elledge, Brass: "IFITM3 inhibits influenza A virus infection by preventing cytosolic entry." in: PLoS pathogens, Vol. 7, Issue 10, pp. e1002337, (2011) (PubMed).

Brass, Huang, Benita, John, Krishnan, Feeley, Ryan, Weyer, van der Weyden, Fikrig, Adams, Xavier, Farzan, Elledge: "The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus." in: Cell, Vol. 139, Issue 7, pp. 1243-54, (2010) (PubMed).
抗原

IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))

别名

Interferon-inducible protein (IFITM3)

背景

The family of interferon-induced transmembrane protein (Ifitm/mil/fragilis) cell surface proteins may modulate cell adhesion and influence cell differentiation.

分子量

14632

基因ID

10410

NCBI登录号

NP_066362

UniProt

Q01628