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IFITM3 抗体 (N-Term)

This anti-IFITM3 antibody is a 兔 多克隆 antibody detecting IFITM3 in WB, IF 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN387989
发货至: 中国

Quick Overview for IFITM3 抗体 (N-Term) (ABIN387989)

抗原

See all IFITM3 抗体
IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))

适用

  • 40
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 33
  • 6
  • 3

克隆类型

  • 34
  • 8
多克隆

标记

  • 30
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IFITM3 antibody is un-conjugated

应用范围

  • 32
  • 22
  • 14
  • 14
  • 10
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB13975
  • 抗原表位

    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Interferon-inducible protein (IFITM3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Interferon-inducible protein (IFITM3).

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:100~500. WB: 1:1000. WB: 1:2000. WB: 1:1000. IHC-P-Leica: 1:100. IHC-P-Leica: 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

    有效期

    6 months
  • Savidis, Perreira, Portmann, Meraner, Guo, Green, Brass: "The IFITMs Inhibit Zika Virus Replication." in: Cell reports, Vol. 15, Issue 11, pp. 2323-30, (2017) (PubMed).

    Mäkelä, Österlund, Westenius, Latvala, Diamond, Gale, Julkunen: "RIG-I Signaling Is Essential for Influenza B Virus-Induced Rapid Interferon Gene Expression." in: Journal of virology, Vol. 89, Issue 23, pp. 12014-25, (2015) (PubMed).

    John, Chin, Perreira, Feeley, Aker, Savidis, Smith, Elia, Everitt, Vora, Pertel, Elledge, Kellam, Brass: "The CD225 domain of IFITM3 is required for both IFITM protein association and inhibition of influenza A virus and dengue virus replication." in: Journal of virology, Vol. 87, Issue 14, pp. 7837-52, (2013) (PubMed).

    Everitt, Clare, Pertel, John, Wash, Smith, Chin, Feeley, Sims, Adams, Wise, Kane, Goulding, Digard, Anttila, Baillie, Walsh, Hume, Palotie, Xue, Colonna, Tyler-Smith, Dunning, Gordon, Smyth, Openshaw et al.: "IFITM3 restricts the morbidity and mortality associated with influenza. ..." in: Nature, Vol. 484, Issue 7395, pp. 519-23, (2012) (PubMed).

    Feeley, Sims, John, Chin, Pertel, Chen, Gaiha, Ryan, Donis, Elledge, Brass: "IFITM3 inhibits influenza A virus infection by preventing cytosolic entry." in: PLoS pathogens, Vol. 7, Issue 10, pp. e1002337, (2011) (PubMed).

    Brass, Huang, Benita, John, Krishnan, Feeley, Ryan, Weyer, van der Weyden, Fikrig, Adams, Xavier, Farzan, Elledge: "The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus." in: Cell, Vol. 139, Issue 7, pp. 1243-54, (2010) (PubMed).

  • 抗原

    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))

    别名

    Interferon-inducible protein (IFITM3)

    背景

    The family of interferon-induced transmembrane protein (Ifitm/mil/fragilis) cell surface proteins may modulate cell adhesion and influence cell differentiation.

    分子量

    14632

    基因ID

    10410

    NCBI登录号

    NP_066362

    UniProt

    Q01628
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