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ATG12 抗体 (N-Term)

Cited in 1 publication. This 兔 多克隆 anti-ATG12 antibody (Clone RB2793) specifically detects ATG12 in IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN387986
发货至: 中国
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Quick Overview for ATG12 抗体 (N-Term) (ABIN387986)

抗原

See all ATG12 抗体
ATG12 (Autophagy Related 12 (ATG12))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This ATG12 antibody is un-conjugated

应用范围

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Immunofluorescence (IF)

克隆位点

RB2793
  • 抗原表位

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    AA 8-38, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ATG12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-38 amino acids from the N-terminal region of human ATG12.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Ma, Huang, Chen, Halliday: "Immunohistochemical evidence for macroautophagy in neurones and endothelial cells in Alzheimer's disease." in: Neuropathology and applied neurobiology, Vol. 36, Issue 4, pp. 312-9, (2010) (PubMed).

  • 抗原

    ATG12 (Autophagy Related 12 (ATG12))

    别名

    ATG12

    背景

    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG12L is the human homolog of yeast APG12, a ubiquitin-activating enzyme E1-like protein essential for the conjugation system that mediates membrane fusion in autophagy.

    分子量

    15113

    基因ID

    9140

    NCBI登录号

    NP_001264712, NP_004698

    UniProt

    O94817

    途径

    Autophagy
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