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JAK2 抗体 (C-Term)

Name: JAK2 抗体 (C-Term)
SKU: ABIN387982
Availability: OutOfStock

This anti-JAK2 antibody is a 兔多克隆 antibody detecting JAK2 in WB, FACS 和 IF. Suitable for 人和小鼠. This Primary Antibody has been cited in 3+ publications.

The anti-JAK2 Pab (ABIN387982 and ABIN2844820) is used in Western blot to detect JAK2 in mouse thymus tissue lysate. (JAK2 抗体 (C-Term))

JAK2 Antibody (C-term) (ABIN387982 and ABIN2844820) flow cytometric analysis of K562 cells (right histogram) compared to a negative control (PBS alone) (left histogram). (JAK2 抗体 (C-Term))

FACS

Confocal immunofluorescent analysis of JAK2 Antibody (C-term) (ABIN387982 and ABIN2844820) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (JAK2 抗体 (C-Term))

3 images

(3 references)

产品编号 ABIN387982

发货至: 中国

Quick Overview for JAK2 抗体 (C-Term) (ABIN387982)

抗原

See all JAK2 抗体

JAK2 (Janus Kinase 2 (JAK2))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This JAK2 antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

RB02956

Discover our top product JAK2 Primary Antibody

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AA 1101-1132, C-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This JAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1101-1132 amino acids from the C-terminal region of human JAK2.

亚型

Ig Fraction
anti-Janus Kinase 2 (JAK2) (pTyr1007), (pTyr1008) antibody
JAK2 适用: 人, 大鼠, 小鼠, 兔, 斑马鱼 WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (AA 508-800) antibody
JAK2 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (AA 916-1103) antibody
JAK2 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (AA 745-955) antibody
JAK2 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5C12C9 unconjugated

anti-Janus Kinase 2 (JAK2) (pTyr221) antibody
JAK2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (pTyr931) antibody
JAK2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (pTyr1007), (pTyr1008) antibody
JAK2 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Monoclonal 1A4 unconjugated Recombinant Antibody

anti-Janus Kinase 2 (JAK2) (C-Term) antibody
JAK2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (AA 1101-1132) antibody
JAK2 适用: 人, 小鼠 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (N-Term) antibody
JAK2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:1000. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Feng, Chen, Wang, Cheng, Zou, Zhong, Xu: "Roflumilast reverses polymicrobial sepsis-induced liver damage by inhibiting inflammation in mice." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 97, Issue 9, pp. 1008-1019, (2017) (PubMed).

Zhao, Li, Liao, Luo, Shi, Feng, Chen: "Evodiamine Induces Apoptosis and Inhibits Migration of HCT-116 Human Colorectal Cancer Cells." in: International journal of molecular sciences, Vol. 16, Issue 11, pp. 27411-21, (2015) (PubMed).

Kanda, Watanabe: "Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes." in: Endocrinology, Vol. 148, Issue 5, pp. 2317-25, (2007) (PubMed).
抗原

JAK2 (Janus Kinase 2 (JAK2))

别名

JAK2

背景

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

分子量

130674

基因ID

3717

NCBI登录号

NP_004963

UniProt

O60674

途径

JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response