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MLL/KMT2A 抗体 (C-Term)

This anti-MLL/KMT2A antibody is a 兔 多克隆 antibody detecting MLL/KMT2A in IHC (p) 和 FACS. Suitable for 人.
产品编号 ABIN387979
发货至: 中国

Quick Overview for MLL/KMT2A 抗体 (C-Term) (ABIN387979)

抗原

See all MLL/KMT2A (MLL) 抗体
MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))

适用

  • 26
  • 12
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宿主

  • 19
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克隆类型

  • 20
  • 6
多克隆

标记

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This MLL/KMT2A antibody is un-conjugated

应用范围

  • 11
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB02951
  • 抗原表位

    • 2
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    • 1
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    AA 3879-3908, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This HRX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3879-3908 amino acids from the C-terminal region of human HRX.

    亚型

    Ig Fraction
  • 应用备注

    IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))

    别名

    HRX

    背景

    The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. Tse et al. (1995) characterized 2 t(1,11)(q21,q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21, AF1Q, in 2 infants with acute myelomonocytic leukemia. In one of these patients, the derivative chromosome 11 represented an in-frame fusion of the N-terminal portion of the MLL gene to the complete AF1Q open reading frame, whereas the derivative chromosome 1 did not give rise to an open reading frame. This observation suggested that the N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23.

    分子量

    431764

    基因ID

    4297

    NCBI登录号

    NP_001184033, NP_005924

    UniProt

    Q03164

    途径

    Warburg Effect
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