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HDAC11 抗体 (C-Term)

This anti-HDAC11 antibody is a 兔 多克隆 antibody detecting HDAC11 in WB 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN387965
发货至: 中国

Quick Overview for HDAC11 抗体 (C-Term) (ABIN387965)

抗原

See all HDAC11 抗体
HDAC11 (Histone Deacetylase 11 (HDAC11))

适用

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人, 小鼠

宿主

  • 48
  • 5

克隆类型

  • 49
  • 4
多克隆

标记

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This HDAC11 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB2589
  • 抗原表位

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    AA 313-345, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This HDAC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-345 amino acids from the C-terminal region of human HDAC11.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

    有效期

    6 months
  • Joshi, Greco, Guise, Luo, Yu, Nesvizhskii, Cristea: "The functional interactome landscape of the human histone deacetylase family." in: Molecular systems biology, Vol. 9, pp. 672, (2013) (PubMed).

    Keedy, Archin, Gates, Espeseth, Hazuda, Margolis: "A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression." in: Journal of virology, Vol. 83, Issue 10, pp. 4749-56, (2009) (PubMed).

  • 抗原

    HDAC11 (Histone Deacetylase 11 (HDAC11))

    别名

    HDAC11

    背景

    HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.

    分子量

    39183

    基因ID

    79885

    NCBI登录号

    NP_001129513, NP_079103

    UniProt

    Q96DB2
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