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HDAC9 抗体 (N-Term)

Name: HDAC9 抗体 (N-Term)
SKU: ABIN387960
Availability: OutOfStock

This anti-HDAC9 antibody is a 兔多克隆 antibody detecting HDAC9 in WB, IF, IP 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 3+ publications.

Both anti-HDAC9 N-term ((ABIN387960 and ABIN2844679)) and C-term ((ABIN387961 and ABIN2844680)) Pab were tested by WB and IP-WB using HeLa and HeLa-HDAC9 transfected cells. (HDAC9 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (HDAC9 抗体 (N-Term))

IHC (p)

Figure 2: Immunofluorescence staining of MITR for a compartmentalization study in undifferentiated C2C12 myoblasts transfected with a MITR-expressing plasmid. (HDAC9 抗体 (N-Term))

This figure shows that both Pab can immunoprecipitate (IP) HDAC9 from HeLa-HDAC9 tranfected cells. (HDAC9 抗体 (N-Term))

Figure 1: Immunoblots for MITR ((ABIN387960 and ABIN2844679) HDAC9 N-term antibody), Mirk, MyoD and tubulin proteins are shown for cytoplasmic (Cyt) and nuclear (N) extracts from undifferentiated C2C12 myoblasts. (HDAC9 抗体 (N-Term))

5 images

(3 references)

产品编号 ABIN387960

发货至: 中国

Quick Overview for HDAC9 抗体 (N-Term) (ABIN387960)

抗原

See all HDAC9 抗体

HDAC9 (Histone Deacetylase 9 (HDAC9))

适用

人

宿主

兔

克隆类型

多克隆

标记

This HDAC9 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB2582

Discover our top product HDAC9 Primary Antibody

抗原表位
13

9

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2

1

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1

1
AA 2-32, N-Term

预测反应

C, M

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This HDAC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-32 amino acids from the N-terminal region of human HDAC9.

亚型

Ig Fraction
anti-Histone Deacetylase 9 (HDAC9) (AA 1-100) antibody
HDAC9 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 9 (HDAC9) (C-Term) antibody
HDAC9 适用: 人, 小鼠, 豚鼠, 绵羊 WB, IHC, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 9 (HDAC9) (AA 2-32) antibody
HDAC9 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 9 (HDAC9) antibody
HDAC9 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 1F2 unconjugated Recombinant Antibody

anti-Histone Deacetylase 9 (HDAC9) (AA 343-569) antibody
HDAC9 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2B7C4 unconjugated

anti-Histone Deacetylase 9 (HDAC9) (AA 23-343) antibody
HDAC9 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 9 (HDAC9) (pSer220), (pSer259) antibody
HDAC9 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 9 (HDAC9) (C-Term) antibody
HDAC9 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 9 (HDAC9) (C-Term) antibody
HDAC9 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 9 (HDAC9) (AA 100-150) antibody
HDAC9 适用: 人, 小鼠, 犬, Cow, 马, Opossum WB 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:1,000. IP: 1:100. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Salian-Mehta, Xu, McKinsey, Tobet, Wierman: "Novel Interaction of Class IIb Histone Deacetylase 6 (HDAC6) with Class IIa HDAC9 Controls Gonadotropin Releasing Hormone (GnRH) Neuronal Cell Survival and Movement." in: The Journal of biological chemistry, Vol. 290, Issue 22, pp. 14045-56, (2015) (PubMed).

Sugo, Oshiro, Takemura, Kobayashi, Kohno, Uesaka, Song, Yamamoto: "Nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth in developing cortical neurons." in: The European journal of neuroscience, Vol. 31, Issue 9, pp. 1521-32, (2010) (PubMed).

Deng, Ewton, Mercer, Friedman: "Mirk/dyrk1B decreases the nuclear accumulation of class II histone deacetylases during skeletal muscle differentiation." in: The Journal of biological chemistry, Vol. 280, Issue 6, pp. 4894-905, (2005) (PubMed).
抗原

HDAC9 (Histone Deacetylase 9 (HDAC9))

别名

HDAC9

背景

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.

分子量

111297

基因ID

9734

NCBI登录号

NP_001191073, NP_001191074, NP_001191075, NP_001191076, NP_001191077, NP_055522, NP_478056, NP_848510, NP_848512

UniProt

Q9UKV0

途径

Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development