HDAC6 抗体 (C-Term)
(3 references)-
- 抗原 See all HDAC6 抗体
- HDAC6 (Histone Deacetylase 6 (HDAC6))
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抗原表位
- AA 1182-1215, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HDAC6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This HDAC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1182-1215 amino acids from the C-terminal region of human HDAC6.
- 克隆位点
- RB5653
- 亚型
- Ig Fraction
- Top Product
- Discover our top product HDAC6 Primary Antibody
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anti-Histone Deacetylase 6 (HDAC6) (AA 560-811) antibody
HDAC6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) antibodyHDAC6 适用: 人, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Histone Deacetylase 6 (HDAC6) antibodyHDAC6 适用: 人, 大鼠, 猴, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 4C5 unconjugated
anti-Histone Deacetylase 6 (HDAC6) (AA 1-200) antibodyHDAC6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) (AA 166-348) antibodyHDAC6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) (AA 1128-1215) antibodyHDAC6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Histone Deacetylase 6 (HDAC6) antibodyHDAC6 适用: 人 WB, ELISA, IP, ICC, FACS 宿主: 小鼠 Monoclonal 236 unconjugated
anti-Histone Deacetylase 6 (HDAC6) antibodyHDAC6 适用: 人 IF, IP, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) (pSer22) antibodyHDAC6 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) (N-Term) antibodyHDAC6 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:2000. IHC-P: 1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "Deacetylation of ?-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly." in: Scientific reports, Vol. 5, pp. 12917, (2015) (PubMed).
: "Acetylproteomic analysis reveals functional implications of lysine acetylation in human spermatozoa (sperm)." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 4, pp. 1009-23, (2015) (PubMed).
: "PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry." in: Journal of cell science, Vol. 126, Issue Pt 6, pp. 1355-65, (2013) (PubMed).
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: "Deacetylation of ?-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly." in: Scientific reports, Vol. 5, pp. 12917, (2015) (PubMed).
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- 抗原
- HDAC6 (Histone Deacetylase 6 (HDAC6))
- 别名
- HDAC6 (HDAC6 产品)
- 背景
- HDAC6 (histone deacetylase 6) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin, and has been shown to interact with HDAC11, SIRT2, and F-actin. HDAC6 is ubiquitinated, but its polyubiquitination however does not lead to degradation. HDAC is also a potential target of sumoylation.
- 分子量
- 131419
- 基因ID
- 10013
- NCBI登录号
- NP_006035
- UniProt
- Q9UBN7
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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