HDAC6 抗体 (C-Term)
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北京 101111
Quick Overview for HDAC6 抗体 (C-Term) (ABIN387955)
抗原
See all HDAC6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1182-1215, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This HDAC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1182-1215 amino acids from the C-terminal region of human HDAC6.
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亚型
- Ig Fraction
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anti-Histone Deacetylase 6 (HDAC6) (AA 560-811) antibody
HDAC6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) (AA 1-200) antibodyHDAC6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) antibodyHDAC6 适用: 人, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Histone Deacetylase 6 (HDAC6) antibodyHDAC6 适用: 人, 大鼠, 猴, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 4C5 unconjugated
anti-Histone Deacetylase 6 (HDAC6) (AA 166-348) antibodyHDAC6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) (AA 1128-1215) antibodyHDAC6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Histone Deacetylase 6 (HDAC6) antibodyHDAC6 适用: 人 WB, ELISA, IP, ICC, ICFC 宿主: 小鼠 Monoclonal 236 unconjugated
anti-Histone Deacetylase 6 (HDAC6) (C-Term) antibodyVerified HDAC6 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) (pSer22) antibodyHDAC6 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) (N-Term) antibodyHDAC6 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000. IHC-P: 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Deacetylation of ?-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly." in: Scientific reports, Vol. 5, pp. 12917, (2015) (PubMed).
: "Acetylproteomic analysis reveals functional implications of lysine acetylation in human spermatozoa (sperm)." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 4, pp. 1009-23, (2015) (PubMed).
: "PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry." in: Journal of cell science, Vol. 126, Issue Pt 6, pp. 1355-65, (2013) (PubMed).
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: "Deacetylation of ?-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly." in: Scientific reports, Vol. 5, pp. 12917, (2015) (PubMed).
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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别名
- HDAC6
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背景
- HDAC6 (histone deacetylase 6) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin, and has been shown to interact with HDAC11, SIRT2, and F-actin. HDAC6 is ubiquitinated, but its polyubiquitination however does not lead to degradation. HDAC is also a potential target of sumoylation.
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分子量
- 131419
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基因ID
- 10013
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NCBI登录号
- NP_006035
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UniProt
- Q9UBN7
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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