KAT5 抗体 (N-Term)
Quick Overview for KAT5 抗体 (N-Term) (ABIN387933)
抗原
See all KAT5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 33-64, N-Term
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预测反应
- M, Rat
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This KAT5 / Tip60/HTATIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-64 amino acids from the N-terminal region of human KAT5 / Tip60/HTATIP.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX." in: Biochemical and biophysical research communications, Vol. 390, Issue 4, pp. 1355-60, (2009) (PubMed).
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: "Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX." in: Biochemical and biophysical research communications, Vol. 390, Issue 4, pp. 1355-60, (2009) (PubMed).
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- KAT5 (K(lysine) Acetyltransferase 5 (KAT5))
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别名
- KAT5 / Tip60/HTATIP
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背景
- HTATIP belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.
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分子量
- 58582
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基因ID
- 10524
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NCBI登录号
- NP_001193762, NP_006379, NP_874368, NP_874369
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UniProt
- Q92993
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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