UBA2 抗体 (C-Term)
Quick Overview for UBA2 抗体 (C-Term) (ABIN387913)
抗原
See all UBA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 601-631, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This SAE2 (UBA2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 601-631 amino acids from the C-terminal region of human SAE2 (UBA2).
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亚型
- Ig Fraction
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anti-SUMO1 Activating Enzyme Subunit 2 (UBA2) (AA 449-564) antibody
UBA2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SUMO1 Activating Enzyme Subunit 2 (UBA2) antibodyUBA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SUMO1 Activating Enzyme Subunit 2 (UBA2) (N-Term) antibodyVerified UBA2 适用: 人, 小鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-SUMO1 Activating Enzyme Subunit 2 (UBA2) (C-Term) antibodyUBA2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SUMO1 Activating Enzyme Subunit 2 (UBA2) (AA 1-640) antibodyUBA2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SUMO1 Activating Enzyme Subunit 2 (UBA2) (N-Term) antibodyUBA2 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SUMO1 Activating Enzyme Subunit 2 (UBA2) antibodyUBA2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SUMO1 Activating Enzyme Subunit 2 (UBA2) (C-Term) antibodyUBA2 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-SUMO1 Activating Enzyme Subunit 2 (UBA2) antibodyUBA2 适用: 人, 大鼠, 犬, 猴 WB, IHC, IF 宿主: 小鼠 Monoclonal 4A3 unconjugated
anti-SUMO1 Activating Enzyme Subunit 2 (UBA2) antibodyUBA2 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))
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别名
- SAE2 (UBA2)
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背景
- Ubiquitin is covalently attached to target proteins by a multienzymatic system consisting of E1 (ubiquitin-activating), E2 (ubiquitin-conjugating), and E3 (ubiquitin-ligating) enzymes. NEDD8, a ubiquitin-like protein, is conjugated to proteins in a manner analogous to ubiquitinylation. beta-amyloid precursor protein-binding protein-1 (APPBP1) can bind to NEDD8 in rabbit reticulocyte lysates. However, since APPBP1 shows similarity to only the N-terminal domain of an E1 enzyme, it must interact with a protein showing similarity to the C-terminal region of E1s. By searching sequence databases, a cDNAs encoding UBA3 was identified as the human homolog of yeast Uba3. The predicted 442-amino acid UBA3 protein shares 43 % sequence identity with yeast Uba3. In vitro, UBA3 formed a complex with APPBP1 and a thioester linkage with NEDD8. APPBP1/UBA3 complex may function as an E1-like enzyme for the activation of NEDD8.
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分子量
- 71224
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基因ID
- 10054
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NCBI登录号
- NP_005490
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UniProt
- Q9UBT2
抗原
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