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Dnmt2 抗体 (AA 346-375)

This anti-Dnmt2 antibody is a 兔 多克隆 antibody detecting Dnmt2 in WB 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN387859
发货至: 中国

Quick Overview for Dnmt2 抗体 (AA 346-375) (ABIN387859)

抗原

See all Dnmt2 (TRDMT1) 抗体
Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

适用

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  • 23
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  • 2
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  • 2
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  • 1
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  • 1
人, 小鼠

宿主

  • 63
  • 7

克隆类型

  • 65
  • 5
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Dnmt2 antibody is un-conjugated

应用范围

  • 43
  • 38
  • 27
  • 13
  • 13
  • 7
  • 7
  • 5
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB1850
  • 抗原表位

    • 15
    • 8
    • 7
    • 7
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    • 6
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    • 1
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    AA 346-375

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This Dnmt2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from human Dnmt2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Lee, Jang, Benoit, Hoque, Califano, Trink, Sidransky, Mao, Moon: "Presence of 5-methylcytosine in CpNpG trinucleotides in the human genome." in: Genomics, Vol. 96, Issue 2, pp. 67-72, (2010) (PubMed).

  • 抗原

    Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

    别名

    Dnmt2

    背景

    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    44597

    基因ID

    1787

    NCBI登录号

    NP_004403

    UniProt

    O14717
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