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PRMT5 抗体 (C-Term)

This anti-PRMT5 antibody is a 兔 多克隆 antibody detecting PRMT5 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN387843
发货至: 中国

Quick Overview for PRMT5 抗体 (C-Term) (ABIN387843)

抗原

See all PRMT5 抗体
PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

适用

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宿主

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克隆类型

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多克隆

标记

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This PRMT5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB0117
  • 抗原表位

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    AA 591-621, C-Term

    预测反应

    B, Pr, M

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This PRMT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 591-621 amino acids from the C-terminal region of human PRMT5.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

    别名

    PRMT5

    背景

    Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

    分子量

    72684

    基因ID

    10419

    NCBI登录号

    NP_001034708, NP_006100

    UniProt

    O14744

    途径

    Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development
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