LRRK2 抗体 (C-Term)
Quick Overview for LRRK2 抗体 (C-Term) (ABIN387804)
抗原
See all LRRK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This PARK8 (LRRK2) antibody was raised in mice using purified His-tagged recombinant protein comprised of the C-terminal 261 residues of LRRK2.
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亚型
- IgG1
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应用备注
- IHC: 1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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Curcumin exposure induces expression of the Parkinson's disease-associated leucine-rich repeat kinase 2 (LRRK2) in rat mesencephalic cells." in: Neuroscience letters, Vol. 468, Issue 2, pp. 120-4, (2009) (PubMed).
: "Dynamic and redundant regulation of LRRK2 and LRRK1 expression." in: BMC neuroscience, Vol. 8, pp. 102, (2008) (PubMed).
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Curcumin exposure induces expression of the Parkinson's disease-associated leucine-rich repeat kinase 2 (LRRK2) in rat mesencephalic cells." in: Neuroscience letters, Vol. 468, Issue 2, pp. 120-4, (2009) (PubMed).
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- LRRK2 (Leucine-Rich Repeat Kinase 2 (LRRK2))
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别名
- PARK8 (LRRK2)
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背景
- This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
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分子量
- 286103
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基因ID
- 120892
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NCBI登录号
- NP_940980
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UniProt
- Q5S007
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development
抗原
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