我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

MAP1LC3A 抗体

Name: MAP1LC3A 抗体
SKU: ABIN387792
Availability: OutOfStock

MAP1LC3A 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 166AT1234 unconjugated

All lanes : Anti-P1LC3A Antibody at dilution Lane 1: Mouse brain whole cell lysate Lane 2: Rat brain whole cell lysate Lane 3: Hun brain whole cell lysate Lysates/proteins at 20 μg per lane.

1 image

(17 references)

产品编号 ABIN387792

发货至: 中国

Datasheet as PDF

抗原 See all MAP1LC3A 抗体

MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
适用
211

105

86

12

9

5

4

3

3

2

2

2

1

1

1

1

1

1
人, 小鼠, 大鼠
宿主
174

43

2
小鼠
Compatible Secondaries
克隆类型
166

53
单克隆
标记
108

18

15

14

14

13

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1
This MAP1LC3A antibody is un-conjugated
应用范围
197

95

73

47

33

32

29

14

14

13

11

10

9

6

5
Western Blotting (WB)

纯化方法

This antibody is purified through a protein G column, followed by dialysis against PBS.

免疫原

This LC3 antibody is generated from mouse immunized with a full length recombinant protein of human LC3 (APG8).

克隆位点

166AT1234

亚型

IgG1 kappa

Top Product

Discover our top product MAP1LC3A Primary Antibody
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 89-120), (cleaved) antibody
MAP1LC3A 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal RB38908 unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-121) antibody
MAP1LC3A 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5B10D8 unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-121) antibody
MAP1LC3A 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5B10D8 unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-30), (N-Term) antibody
MAP1LC3A 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7481 unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) antibody
MAP1LC3A 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-120) antibody
MAP1LC3A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-121) antibody
MAP1LC3A 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) antibody
MAP1LC3A 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 166AT1234 unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-30), (N-Term), (pSer12) antibody
MAP1LC3A 适用: 人 WB, DB, EIA 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) antibody
MAP1LC3A 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 5G10 unconjugated

应用备注

WB: 1:8000

限制

仅限研究用
状态

Liquid

缓冲液

Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze-thaw cycles.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

有效期

6 months
Ichikawa, Alves, Pfeiffer, Langa, Hernández-Santana, Suzuki, Prehn, Engel, Henshall: "Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice." in: Cell death & disease, Vol. 8, Issue 1, pp. e2556, (2017) (PubMed).

Griesser, Vemula, Raulien, Wagner, Reeg, Grune, Fedorova: "Cross-talk between lipid and protein carbonylation in a dynamic cardiomyocyte model of mild nitroxidative stress." in: Redox biology, Vol. 11, pp. 438-455, (2017) (PubMed).

Chen, Fang, Su, Hsu, Yang, Huang: "Lapatinib induces autophagic cell death and differentiation in acute myeloblastic leukemia." in: OncoTargets and therapy, Vol. 9, pp. 4453-64, (2016) (PubMed).

Graham, Kaza, Klocke, Gillespie, Shevde, Carroll, Roth: "Tamoxifen Induces Cytotoxic Autophagy in Glioblastoma." in: Journal of neuropathology and experimental neurology, Vol. 75, Issue 10, pp. 946-954, (2016) (PubMed).

He, Yuan, Qi, Zhang, Wang: "Atorvastatin induces autophagic cell death in prostate cancer cells in vitro." in: Molecular medicine reports, Vol. 11, Issue 6, pp. 4403-8, (2015) (PubMed).

Vlahava, Eliopoulos, Sourvinos: "CD40 ligand exhibits a direct antiviral effect on Herpes Simplex Virus type-1 infection via a PI3K-dependent, autophagy-independent mechanism." in: Cellular signalling, Vol. 27, Issue 6, pp. 1253-63, (2015) (PubMed).

Hsin, Ou, Wu, Jan, Hsiao, Lin, Ko: "GMI, an Immunomodulatory Protein from Ganoderma microsporum, Potentiates Cisplatin-Induced Apoptosis via Autophagy in Lung Cancer Cells." in: Molecular pharmaceutics, Vol. 12, Issue 5, pp. 1534-43, (2015) (PubMed).

Rabionet, Bayerle, Jennemann, Heid, Fuchser, Marsching, Porubsky, Bolenz, Guillou, Gröne, Gorgas, Sandhoff: "Male meiotic cytokinesis requires ceramide synthase 3-dependent sphingolipids with unique membrane anchors." in: Human molecular genetics, Vol. 24, Issue 17, pp. 4792-808, (2015) (PubMed).

Kashima, Shintani-Ishida, Nakajima, Maeda, Unuma, Uchiyama, Yoshida: "Immunohistochemical study of the autophagy marker microtubule-associated protein 1 light chain 3 in normal and steatotic human livers." in: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 44, Issue 7, pp. 779-87, (2014) (PubMed).

Islam, Shin, Yun, Cho, Seo, Chae, Cho: "The effect of RNAi silencing of p62 using an osmotic polysorbitol transporter on autophagy and tumorigenesis in lungs of K-rasLA1 mice." in: Biomaterials, Vol. 35, Issue 5, pp. 1584-96, (2013) (PubMed).

Zhang, Morgan, Chen, Choksi, Liu: "Induction of autophagy is essential for monocyte-macrophage differentiation." in: Blood, Vol. 119, Issue 12, pp. 2895-905, (2012) (PubMed).

Zhou, Kang, Spector: "Production of interferon ? by human immunodeficiency virus type 1 in human plasmacytoid dendritic cells is dependent on induction of autophagy." in: The Journal of infectious diseases, Vol. 205, Issue 8, pp. 1258-67, (2012) (PubMed).

Xing, Zhang, Li, Zhang, Li, Dang, Li, Fan, Yu, Pei, Zeng: "Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction." in: Autophagy, Vol. 8, Issue 1, pp. 63-76, (2012) (PubMed).

Song, Lee: "Mouse knock-out of IOP1 protein reveals its essential role in mammalian cytosolic iron-sulfur protein biogenesis." in: The Journal of biological chemistry, Vol. 286, Issue 18, pp. 15797-805, (2011) (PubMed).

Tuffy, Concannon, DOrsi, King, Woods, Huber, Ward, Prehn: "Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition." in: Molecular and cellular biology, Vol. 30, Issue 23, pp. 5484-501, (2010) (PubMed).

Rouschop, van den Beucken, Dubois, Niessen, Bussink, Savelkouls, Keulers, Mujcic, Landuyt, Voncken, Lambin, van der Kogel, Koritzinsky, Wouters: "The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5." in: The Journal of clinical investigation, Vol. 120, Issue 1, pp. 127-41, (2010) (PubMed).

Byun, Yoon, An, Park, Kang, Kim, Lee: "The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras." in: Carcinogenesis, Vol. 30, Issue 11, pp. 1880-8, (2009) (PubMed).
抗原

MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

别名

LC3 (MAP1LC3A 产品)

别名

ATG8E antibody, LC3 antibody, LC3A antibody, MAP1ALC3 antibody, MAP1BLC3 antibody, 1010001H21Rik antibody, 4922501H04Rik antibody, LC3a antibody, MGC69006 antibody, zgc:77094 antibody, MGC89867 antibody, MAP1LC3A antibody, map1lc3a antibody, microtubule associated protein 1 light chain 3 alpha antibody, microtubule-associated protein 1 light chain 3 alpha antibody, microtubule associated protein 1 light chain 3 alpha S homeolog antibody, MAP1LC3A antibody, Map1lc3a antibody, map1lc3a.S antibody, map1lc3a antibody

背景

MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene.

基因ID

84557

NCBI登录号

NP_115903, NP_852610

UniProt

Q9H492, Q9GZQ8

途径

Autophagy