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Nanog 抗体

This anti-Nanog antibody is a 小鼠 单克隆 antibody detecting Nanog in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN387791
发货至: 中国

Quick Overview for Nanog 抗体 (ABIN387791)

抗原

See all Nanog (NANOG) 抗体
Nanog (NANOG) (Nanog Homeobox (NANOG))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Nanog antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

60CT77-1-1
  • 纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    This NANOG monoclonal antibody is generated from mouse immunized with NANOG recombinant protein.

    亚型

    IgG1 kappa
  • 应用备注

    WB: 1:100~250. WB: 1:100~250. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    Nanog (NANOG) (Nanog Homeobox (NANOG))

    别名

    NANOG

    背景

    Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).

    分子量

    34620

    基因ID

    79923

    NCBI登录号

    NP_079141

    UniProt

    Q9H9S0

    途径

    Stem Cell Maintenance
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