MLH1 抗体
Quick Overview for MLH1 抗体 (ABIN379237)
抗原
See all MLH1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The G168-15 antibody recognizes the human and mouse MLH1 (80-85 kDa. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC). MSH-2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process. It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair. cross reacts with human, hamster and rat
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免疫原
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Full length recombinant MLH.
Type of Immunogen: Recombinant protein -
亚型
- IgG1
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anti-MutL Homolog 1 (MLH1) (AA 1-756) antibody
MLH1 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal M1 unconjugated
anti-MutL Homolog 1 (MLH1) (AA 381-483) antibodyMLH1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7A7C8 unconjugated
anti-MutL Homolog 1 (MLH1) (AA 381-483) antibodyMLH1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 8C12B7 unconjugated
anti-MutL Homolog 1 (MLH1) (AA 350-519) antibodyMLH1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 1 (MLH1) (AA 381-483) antibodyMLH1 适用: 人, 猴 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 4C9C7 unconjugated
anti-MutL Homolog 1 (MLH1) (Internal Region) antibodyMLH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 1 (MLH1) antibodyMLH1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 1 (MLH1) (AA 501-600) antibodyMLH1 适用: 人 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 1 (MLH1) (Internal Region) antibodyMLH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 1 (MLH1) (AA 373-735) antibodyMLH1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Supplied as a liquid containing sodium azide as a preservative
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- MLH1 (MutL Homolog 1 (MLH1))
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别名
- MLH1
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背景
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Name/Gene ID: MLH1
Synonyms: MLH1, COCA2, FCC2, HMLH1, HNPCC, HNPCC2, MutL protein homolog 1 -
基因ID
- 4292
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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