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MSH6 抗体

MSH6 适用: 人, 小鼠, 大鼠, 犬 WB, IP 宿主: 小鼠 Monoclonal 44 unconjugated
产品编号 ABIN379235
发货至: 中国
  • 抗原 See all MSH6 抗体
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    适用
    • 77
    • 34
    • 28
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 58
    • 16
    • 3
    小鼠
    克隆类型
    • 46
    • 31
    单克隆
    标记
    • 45
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MSH6 antibody is un-conjugated
    应用范围
    • 52
    • 27
    • 25
    • 20
    • 14
    • 13
    • 12
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    特异性
    MSH6 is a heterodimer of MSH2 and binds to DNA containing G/T mismatches. The MSH2-MSH6 complex recognizes a single-based mispair insertion/deletion loop. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related human carcinogenesis. Studies have shown the mutations of MLH-1, MSH2 and MSH6 genes contribute to the development of sporadic colorectal carcinoma. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. cross reacts with mouse, rat and dog.
    纯化方法
    Purified
    免疫原
    Synthetic human MSH6 peptide.

    Type of Immunogen: Synthetic peptide
    克隆位点
    44
    亚型
    IgG1
    Top Product
    Discover our top product MSH6 Primary Antibody
  • 应用备注
    Approved: IP, WB (1:100 - 1:500)
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Buffer contains: 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    别名
    MSH6 (MSH6 产品)
    别名
    GTBP antibody, GTMBP antibody, HNPCC5 antibody, HSAP antibody, p160 antibody, cb326 antibody, wu:fb36c12 antibody, LOC100227810 antibody, AU044881 antibody, AW550279 antibody, Gtmbp antibody, mutS homolog 6 antibody, mutS homolog 6 (E. coli) antibody, DNA mismatch repair protein antibody, MSH6 antibody, msh6 antibody, Msh6 antibody
    背景
    Name/Gene ID: MSH6

    Synonyms: MSH6, GTBP, HSAP, GTMBP, MutS (E. coli) homolog 6, HMSH6, Sperm-associated protein, p160, G/T mismatch-binding protein, HNPCC5, MutS homolog 6 (E. coli), MutS-alpha 160 kDa subunit
    基因ID
    2956
    途径
    DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
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