CD74 抗体
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北京 101111
Quick Overview for CD74 抗体 (ABIN376401)
抗原
See all CD74 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Anti-Human CD74-LE/AF
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特异性
- Human CD74, Mr 41, 35, 33 kDa
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产品特性
- Low Endotoxin/Azide Free Anti-Human CD74 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, and blocking assays.
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内毒素水平
- Low Endotoxin
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免疫原
- Cell line SU-DHL-4 nuclei
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate buffered saline, pH 7.4
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储存液
- Azide free
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注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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储存条件
- 4 °C
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储存方法
- 2-8°C
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- CD74 (HLA-DR-gamma (CD74))
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别名
- CD74
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背景
- CD74 represents a type II integral membrane protein known as MHC Class II-associated invariant chain (Mr 43, 41, 35, 33 kDa). It is moderately expressed on B cells, and weakly on monocytes and macrophages. CD74 is also found on a subset of activated T cells, Langerhans cells, dendritic cells and some epithelial cells. CD74 may play a role in antigen processing and presentation through intracellular transport and expression of Class II molecules on the cell surface.
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基因ID
- 972
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UniProt
- P04233
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途径
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
抗原
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