CD11b 抗体 (PE-Cy7)
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- 抗原 See all CD11b (ITGAM) 抗体
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD11b antibody is conjugated to PE-Cy7
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Mouse CD11b, Mr 170 kDa
- 产品特性
- Rat Anti-Mouse CD11b-PE/CY7
- 纯化方法
- Purified
- 免疫原
- Peritoneal macrophages from B6D2 hybrid mice
- 克隆位点
- 3A33
- 亚型
- IgG2a
- Top Product
- Discover our top product ITGAM Primary Antibody
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- 应用备注
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Block - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, and AF488 conjugates 1 g/106 cells PE, APC, SPRD, CY5, PE/CY7, APC/CY7, and AF700 conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- 样本量
- 1 mL
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- 0.1 mg in 0.2 mL of PBS/Sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
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Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C
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- 抗原
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- 别名
- CD11b (ITGAM 产品)
- 背景
- CD11b (integrin α M subunit) combines with CD18 (integrin β 2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.
- 途径
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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