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LAMP1 抗体 (Biotin)

LAMP1 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal H4A3 Biotin
产品编号 ABIN375425
发货至: 中国
  • 抗原 See all LAMP1 抗体
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
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    小鼠
    克隆类型
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    单克隆
    标记
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    This LAMP1 antibody is conjugated to Biotin
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (IHC)
    特异性
    Human/Rhesus/African Green Monkey/Pigtail Macaque/Sooty Mangabey CD107a, Mr 100-120 kDa
    产品特性
    Mouse Anti-Human CD107a-BIOT
    纯化方法
    Purified
    免疫原
    Human adherent peripheral blood cells
    克隆位点
    H4A3
    亚型
    IgG1
    Top Product
    Discover our top product LAMP1 Primary Antibody
  • 应用备注
    Working Dilution:
    10 µL/10^6 cells
    Representative data are included in this product insert.

    Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
    限制
    仅限研究用
  • 注意事项
    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
  • Hershkovitz, Rosental, Rosenberg, Navarro-Sanchez, Jivov, Zilka, Gershoni-Yahalom, Brient-Litzler, Bedouelle, Ho, Campbell, Rager-Zisman, Despres, Porgador: "NKp44 receptor mediates interaction of the envelope glycoproteins from the West Nile and dengue viruses with NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 4, pp. 2610-21, (2009) (PubMed).

  • 抗原
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
    别名
    CD107a (LAMP1 产品)
    别名
    CD107a antibody, LAMPA antibody, LGP120 antibody, AI196048 antibody, Lamp-1 antibody, LEP100 antibody, LAMP-1 antibody, LGP-A antibody, Lgpa antibody, Lysosome-associated membrane protein 1 antibody, cd107a antibody, lamp-1 antibody, lamp1 antibody, lampa antibody, lgp120 antibody, rexp76 antibody, lysosomal associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 L homeolog antibody, LAMP1 antibody, Lamp1 antibody, lamp1.L antibody
    背景
    CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is expressed by granulocytes, T cells, macrophages, dendritic cells, activated platelets, tonsillar epithelium and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential, where they may increase adhesion to extracellular matrix and endothelium.
    途径
    Autophagy
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