GPI 抗体 (pSer185)
Quick Overview for GPI 抗体 (pSer185) (ABIN375349)
抗原
See all GPI 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer185
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特异性
- Reacts with human 65 kDa GPI protein with a phosphoserine at position 185
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交叉反应 (详细)
- Do not cross react with non-phospho GPI protein.
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纯化方法
- Antiserum
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免疫原
- Synthetic peptide derived from human GPI containing a phosphoserine at position 185
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亚型
- IgG
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/200 to 1/1 000 - WB : 1/500 to 1/5 000 -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Must be reconstituted in distilled water.
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储存条件
- 4 °C/-20 °C
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储存方法
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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有效期
- 24 months
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- GPI (Glucose-6-Phosphate Isomerase (GPI))
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背景
- Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Phosphorylation at Ser-185 by CK2 has been shown to decrease enzymatic activity and may contribute to secretion by a non-classical secretory pathway.
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UniProt
- P06744
抗原
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