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GPI 抗体 (pSer185)

This anti-GPI antibody is a 兔 多克隆 antibody detecting GPI in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN375349
发货至: 中国

Quick Overview for GPI 抗体 (pSer185) (ABIN375349)

抗原

See all GPI 抗体
GPI (Glucose-6-Phosphate Isomerase (GPI))

适用

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宿主

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克隆类型

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多克隆

标记

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This GPI antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    pSer185

    特异性

    Reacts with human 65 kDa GPI protein with a phosphoserine at position 185

    交叉反应 (详细)

    Do not cross react with non-phospho GPI protein.

    纯化方法

    Antiserum

    免疫原

    Synthetic peptide derived from human GPI containing a phosphoserine at position 185

    亚型

    IgG
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    - IHC : 1/200 to 1/1 000 - WB : 1/500 to 1/5 000

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Must be reconstituted in distilled water.

    储存条件

    4 °C/-20 °C

    储存方法

    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

    有效期

    24 months
  • 抗原

    GPI (Glucose-6-Phosphate Isomerase (GPI))

    背景

    Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Phosphorylation at Ser-185 by CK2 has been shown to decrease enzymatic activity and may contribute to secretion by a non-classical secretory pathway.

    UniProt

    P06744
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